GEO series

Identification of a B cell signature associated with renal transplant Tolerance in humans

GSE22229 Homo sapiens Expression profiling by array 58 samples Submitted 2010/06/09 Platform GPL570

Summary

In this study, investigators recruited the largest reported cohort of tolerant kidney transplant recipients who maintained their graft after ceasing to take their immunosuppression drug, and compared this cohort to subjects with stable allograft function while on immunosuppression and healthy non transplated, controls. Using gene expression studies, they identified genetic markers that are strong candidates for predicting kidney transplant candidates who may benefit from minimization or withdrawl of immunosuppression. Microarrays were used to detect expressed gene profiles of whole-blood total RNA from subjects in the tolerant, standard immunotherapy and healthy control participants

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Direct links to NCBI, no account and no request form: the whole study as GSE22229_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 58 samples.

Whole study · RAW.tar ↓ Series matrix ↓ All supplementary files ↗

Also filed as BioProject PRJNA128837. Searching any of these in the dataset finder brings you back here.

NCBI GEO page ↗ Paper (PMID 20501946) ↗

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