Krüppel-like factor 4 and 5 oppositely determine neural precursor cell fate in the developing mammalian brain
RNA-seq (gene expression) · mouse · 11 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 11 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Klf5 Regulates the Transition from Apical Radial Glia to Intermediate Progenitor Cells in the Developing Mammalian BrainThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE222950_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA924273 and SRA study SRP417714. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 11 more — browse all 11 samples with per-sample file links →
- GSE247069 Self-organised pattern formation in the developing dorsal neural tube by a temporal relay of BMP signalling 48 samples shares developing, neural
- GSE288114 Krüppel-like factor 2 programs early exhausted T cell states and restrains antiviral immunity [RNA-Seq] 32 samples shares ppel-like, factor
- GSE233856 A single cell transcriptomic map of the developing Atoh1-lineage uncovers neural fate decisions and neuronal diversity in the hindbrain.[RNA-Seq] 24 samples shares developing, neural
- GSE288281 Krüppel-like Factor family members control expression of genes required for serous cavity and alveolar macrophage identities [RNA-seq] 19 samples shares ppel-like, factor
- GSE253103 Identification of distinct mesenchymal factors in the developing bladder and urethra 16 samples shares developing, factor
- GSE243373 Genome-wide 5mC and 5hmC patterns determine unique transcriptional signatures,regulators and exon inclusion of neural cell types in mouse brain [RNA-Seq] 15 samples shares determine, neural
- GSE275615 Identification of distinct epithelial factors in the developing mouse bladder and urethra (E14.5 and E18.5) 14 samples shares developing, factor
- GSE275616 Identification of distinct mesenchymal factors in the developing mouse bladder and urethra (E14.5 and E18.5) 12 samples shares developing, factor
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.