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Long-read nanopore sequencing (Nanopore-seq) of PQBP1 knockdown in ovarian cancer cells

GSE223088 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2024/05/01 Platform GPL26167
Summary
To investigate the comprehensive function of PQBP1 in the regulation of RNA splicing, we established Dox-inducible PQBP1 knockdown HEY cell line. We then performed transcript expression profiling analysis using data obtained from long-read nanopore-seq of PQBP1 knockdown and control HEY cells (three biological replications of each sample).
Published in
Splicing Factor PQBP1 Curtails BAX Expression to Promote Ovarian Cancer Progression
Liu X, Zhang J, Wang Z et al. · Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 · PMID 38342602 · doi:10.1002/advs.202306229
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Also filed as BioProject PRJNA924816 and SRA study SRP417944. Searching any of these in the dataset finder brings you back here.

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