GEO series
ETMR stem-like state and chemo-resistance are supported by perivascular cells at single-cell resolution (human organoids subset)
GSE224476
Homo sapiens
Expression profiling by high throughput sequencing
12 samples
2025/04/16
GPL30173
Summary
To investigate the celluar heterogeneity of ETMR and the role of pericytes in the tumor microenvironment, we performed single-cell RNA sequencing of about 140,000 cells from primary human and murine ETMR as well as from 2D ETMR cultures and 3D models of ETMR-harboring forebrain organoids. We also analysed 3 ETMR human samples by spatial transcriptomics.
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Paper (PMID 40562749) ↗
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