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Z-DNA underlies the target choice of Aire by facilitating promoter poising [ChIP-seq]

GSE224553 Mus musculus Genome binding/occupancy profiling by high throughput sequencing 7 samples Submitted 2024/03/11 Platform GPL19057Platform GPL17021
Summary
We profiled Pol II binding in medullary thymic epithelial cells using ChIP-seq to investigate the logic of Aire's target choices
Published in
AIRE relies on Z-DNA to flag gene targets for thymic T cell tolerization
Fang Y, Bansal K, Mostafavi S et al. · Nature 2024 · PMID 38480882 · doi:10.1038/s41586-024-07169-7
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Also filed as BioProject PRJNA934442 and SRA study SRP424167. Searching any of these in the dataset finder brings you back here.

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