GEO series
PCBP1 regulates transcription by binding ssDNA at promoters
GSE225637
Homo sapiens
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
12 samples
2025/05/01
GPL24676
Summary
To investigate the role of PCBP1 in transcription through its ability to bind DNA, we performed a CRISPR knockout of PCBP1 in A549 lung adenocarcinoma cells and generated a genome wide map of PCBP1's DNA binding using CUT&RUN. We used RNA-seq of A549 WT cells and two A549 PCBP1 KO cell lines we generated to quantify gene expression changes. We used PCBP1 CUT&RUN to generate a map of PCBP1's DNA binding sites.
Download
NCBI GEO page ↗
Paper (PMID 39342995) ↗
{# Names what the click gives you. "Open in finder" meant nothing to a
visitor who arrived from a search engine and has never seen the tool. #}
Find more
human RNA-seq datasets →
Similar datasets
- GSE300595 Multiomic sequencing identifies myeloid cell associations with neoadjuvant chemotherapy treatment response in pancreatic adenocarcinoma (PDAC) 24 samples
- GSE335464 Integrative single-cell multi-omics profiling of human pancreatic islets identifies T1D-associated genes and regulatory signals [single cell] 28 samples
- GSE307120 Fusion-driven oncogenic programs shape the immune landscape in translocation renal cell carcinoma 21 samples
- GSE263717 Epigenomic profiles of SLE resting and transitional B cells 150 samples
- GSE241581 DCAF15 control of cohesin dynamics sustains acute myeloid leukemia 36 samples
- GSE233321 Single-cell map of the healthy human immune system across the lifespan reveals unique infant immune signatures 118 samples
- GSE283005 Distinct differentiation trajectories leave lasting impacts on gene regulation and function of V2a neurons 60 samples
- GSE342612 Transcriptomic and H3K27ac chromatin responses of human microglia to acute PFOS exposure and recovery 36 samples
Share this dataset
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.