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RNA sequencing for wild type and shENO1 Daudi cells.

GSE225685 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2024/06/18 Platform GPL24676
Summary
We systematically evaluated the expression pattern and function of ENO1 in BL and clarified that ENO1, regulated by cMyc, can promote BL cell proliferation and metastasis by activating TGFβ1 signaling pathways in a plasmin-mediated manner. Through structure-based virtual screening, we successfully discovered Ciwujianoside E (L-06) as a novel ENO1 inhibitor which can limit BL cell proliferation and dissemination in vitro and in vivo.
Published in
ENO1-related gene signature predicts prognosis and therapeutic response in diffuse large B-cell lymphoma
Yan W, Liu X, Gao B et al. · Frontiers in immunology 2025 · PMID 41208958 · doi:10.3389/fimmu.2025.1644020
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Also filed as BioProject PRJNA937163 and SRA study SRP423679. Searching any of these in the dataset finder brings you back here.

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