GEO series
Disruption of RNAPII transcription elongation links Oncogenic splicing factor mutations to replciation stress and targetable alterations in chromatin landscape [Ser2PRNAPII ChIP-seq]
GSE225995
Homo sapiens
Genome binding/occupancy profiling by high throughput sequencing
29 samples
2024/03/12
GPL16791
Summary
To investigate changes in the elongating form of RNA Polymerase II across different conditions, we peformed ChIP-seq using antibody against the Ser2P RNAPII of pTEFb in K562 cells at 4 days after modified allele expression We then performed coverage plot analyses using data obtained from ChIP-seq from IP and Input fractions to investigate Ser2P RNAPII distribution changes
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NCBI GEO page ↗
Paper (PMID 38521065) ↗
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