Extracellular matrix derived from dental pulp stem cells promotes osteogenic differentiation of gingival fibroblasts via Wnt and Hippo signaling pathway
RNA-seq (gene expression) · human · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 12 samples: 3 × N-dECM_DPSCs vs 3 × OM-dECM_DPSCs vs 3 × N-dECM_GSCs vs 3 × OM-dECM_GSCsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Human dental pulp stem cells derived extracellular matrix promotes mineralization via Hippo and Wnt pathwaysScientific reports · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE226347_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA939905 and SRA study SRP425062. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7073711 N-dECM_DPSCs1 N-dECM_DPSCs
- GSM7073712 N-dECM_DPSCs2 N-dECM_DPSCs
- GSM7073713 N-dECM_DPSCs3 N-dECM_DPSCs
- GSM7073714 OM-dECM_DPSCs1 OM-dECM_DPSCs
- GSM7073715 OM-dECM_DPSCs2 OM-dECM_DPSCs
- GSM7073716 OM-dECM_DPSCs3 OM-dECM_DPSCs
- GSM7073717 N-dECM_GSCs1 N-dECM_GSCs
- GSM7073718 N-dECM_GSCs2 N-dECM_GSCs
- GSM7073719 N-dECM_GSCs3 N-dECM_GSCs
- GSM7073720 OM-dECM_GSCs1 OM-dECM_GSCs
- GSM7073721 OM-dECM_GSCs2 OM-dECM_GSCs
- GSM7073722 OM-dECM_GSCs3 OM-dECM_GSCs
- GSE309392 Cancer-associated fibroblasts promote esophageal carcinogenesis and lung metastasis by CDH11-mediated extracellular matrix environment remodeling [scRNA-Seq] 23 samples shares extracellular, fibroblasts, matrix
- GSE208732 Mapping functional to morphological variation reveals the basis of regional extracellular matrix subversion and nerve invasion in pancreatic cancer [RNA-seq] 102 samples shares extracellular, matrix
- GSE200492 Transcriptomic Landscape of Human iPSCs-derived Osteogenic Differentiation Identifies a Key Regulator, KLF16 60 samples shares osteogenic, derived
- GSE273882 Arginine Promotes The Activation of Human Lung Fibroblasts Independent of Its Metabolism 52 samples shares fibroblasts, promotes
- GSE301181 Identification of IPF Specific Genes Expressed by Lung Tissue - Derived Fibroblasts Using Next Generation Sequencing 43 samples shares fibroblasts, derived
- GSE289930 Proteogenomic Characterization of Primary Oral Cancer Unveils Extracellular Matrix Remodeling and Immunosuppressive Microenvironment Linked to Lymph Node Metastasis [RNA-seq] 33 samples shares extracellular, matrix
- GSE316027 β-hydroxybutyrate-driven histone lysine β-hydroxybutyrylation promotes the immunostimulatory activity of monocyte-derived macrophages in rectal cancer 32 samples shares promotes, derived
- GSE314750 Increased arrhythmic risk in obesity is transduced by adipose tissue-derived extracellular vesicles 30 samples shares extracellular, derived
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.