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Targeting PELP1 reduces endometrial cancer progression via attenuation of ribosomal biogenesis

GSE226850 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2024/10/16 Platform GPL24676
Summary
We examined the mechanisms by which SMIP34 regulates EEC progression. EEC cells (HEC-1-A) were treated with either vehicle or SMIP34 20µM for 24 hours, and total RNA was isolated for RNA-seq analysis. Our results demonstrated that PELP1 inhibition by SMIP34 reduces the expression of genes involved in ribosome biogenesis and translation.
Published in
PELP1 inhibition by SMIP34 reduces endometrial cancer progression via attenuation of ribosomal biogenesis
Yang X, Liu Z, Tang W et al. · Molecular oncology 2024 · PMID 37853941 · doi:10.1002/1878-0261.13539
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Also filed as BioProject PRJNA941881 and SRA study SRP425988. Searching any of these in the dataset finder brings you back here.

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