GEO series
Estrogen Effects on Abdominal Skeletal Muscle Fibroblasts in Inguinal Hernia Mouse Model [ATAC-Seq]
GSE226860
Mus musculus
Genome binding/occupancy profiling by high throughput sequencing
12 samples
2025/03/19
GPL24247
Summary
Humanized aromatase mice spontaneously develop hernias caused by fibrosis of lower abdominal skeletal muscle. To understand the estrogen action leading to herniation, fibroblasts were isolated and cultured under estrogen-replete and deplete conditions.
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Paper (PMID 39903526) ↗
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