Role of progesterone receptor in inguinal hernia formation via skeletal muscle fibrosis [Hernia_Multiomics]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 20 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 20 samples: 20 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Role of progesterone action in inguinal hernia formation via skeletal muscle fibrosis and atrophyJCI insight · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE288662_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1218814 and SRA study SRP561369. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 20 sample titles: 20 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8772685 Multiome, Veh Sample 1, ATAC
- GSM8772686 Multiome, Veh Sample 1, GEX
- GSM8772687 Multiome, Veh Sample 2, ATAC
- GSM8772688 Multiome, Veh Sample 2, GEX
- GSM8772689 Multiome, Veh Sample 3, ATAC
- GSM8772690 Multiome, Veh Sample 3, GEX
- GSM8772691 Multiome, EP Sample 1, ATAC
- GSM8772692 Multiome, EP Sample 1, GEX
- GSM8772693 Multiome, EP Sample 2, ATAC
- GSM8772694 Multiome, EP Sample 2, GEX
- GSM8772695 Multiome, EP Sample 3, ATAC
- GSM8772696 Multiome, EP Sample 3, GEX
- GSM8772697 Multiome, EP Sample 4, ATAC
- GSM8772698 Multiome, EP Sample 4, GEX
- GSM8772699 Multiome, EPR Sample 1, ATAC
- GSM8772700 Multiome, EPR Sample 1, GEX
- GSM8772701 Multiome, EPR Sample 2, ATAC
- GSM8772702 Multiome, EPR Sample 2, GEX
- GSM8772703 Multiome, EPR Sample 3, ATAC
- GSM8772704 Multiome, EPR Sample 3, GEX
- GSE253735 Loss of skeletal muscle Bmal1 +/- Exercise Training [Mouse liver, heart, inguinal white adipose and lung tissues 64 samples shares inguinal, skeletal, muscle
- GSE314584 Toll-Like-Receptor 5 Reduces Lung Dysbiosis and Protects Against Pulmonary Fibrosis 124 samples shares receptor, fibrosis
- GSE266438 Loss of Sphingosine-1-Phosphate Receptor 4 weakens innate mechanisms leading to defective lymph node hypertrophy and germinal center formation 45 samples shares formation, receptor
- GSE261166 Transcription factor 21 regulates cardiac myofibroblast formation and fibrosis [RNA-Seq] 16 samples shares formation, fibrosis
- GSE263602 The p75 neurotrophin receptor regulates the skeletal stem cell niche through sensory innervation 14 samples shares receptor, skeletal
- GSE306265 Astrocyte glucocorticoid receptor signaling restricts neuronal plasticity 106 samples shares receptor
- GSE267452 Loss of Nuclear Receptor Nr4a3 Alleviates Cellular Senescence to Promote Adult Direct Cardiac Reprogramming 54 samples shares receptor
- GSE291449 T cell receptor signaling induces expression of lysine demethylase KDM6B to maintain Treg homeostasis 46 samples shares receptor
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.