Transcriptional regulation of microglia priming by IRF7, IRF9 and SMAD3 in accelerated aging mice
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 24 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 24 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE227607_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA945895 and SRA study SRP427880. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 24 more — browse all 24 samples with per-sample file links →
- GSE227606 Transcriptional regulation of microglia priming by IRF7, IRF9 and SMAD3 in accelerated aging mice [RNA-seq] 16 samples shares smad3, irf7, irf9, accelerated, microglia, priming, aging
- GSE227605 Transcriptional regulation of microglia priming by IRF7, IRF9 and SMAD3 in accelerated aging mice [ATAC-seq] 8 samples shares smad3, irf7, irf9, accelerated, microglia, priming, aging
- GSE307881 Mouse Offspring Conceived by In Vitro Fertilization Exhibit Accelerated Reproductive Aging Through Early Ovarian Failure 151 samples shares accelerated, aging
- GSE282066 Accelerated Midlife Endocrine and Bioenergetic Brain Aging in APOE4 Female Mice 59 samples shares accelerated, aging
- GSE289566 Ultra-resolution, multiscale live imaging reveals TADs as domains of cohesin-accelerated search 13 samples shares accelerated, aging
- GSE266485 A disease similarity approach identifies short-lived Niemann-Pick type C disease mice with accelerated brain aging as a novel mouse model for Alzheimer’s disease and aging research 12 samples shares accelerated, aging
- GSE315433 Versatile SMAD2 and SMAD3 epitope-tagged mouse models for genome-wide profiling of TGFβ superfamily signaling: uncovering novel GDF9-SMAD2/3 target genes 44 samples shares smad3
- GSE264034 IRF7 promotes systemic autoimmunity by transcriptionally regulating B cell differentiation through germinal center and plasma cell pathways [ChIP-seq] 4 samples shares irf7
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.