H3K27ac and H3K4me3 ChIP-Seq profiling of a human paired left and right atrial cohort of atrial fibrillation and healthy sinus rhythm individuals
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 52 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 52 samples: 51 distinct titles, 1 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- An epigenomic investigation of atrial fibrillation in a matched left and right atrial human cohortClinical epigenetics · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE227793_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA947086 and SRA study SRP429018. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 52 sample titles: 51 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7108228 left cardiac atrium, sinus rhythm, H3K27ac, 12b, vl0026
- GSM7108229 right cardiac atrium, sinus rhythm, H3K27ac, 12b, vl0027
- GSM7108230 left cardiac atrium, atrial fibrillation, H3K27ac, 25, vl0028
- GSM7108231 right cardiac atrium, atrial fibrillation, H3K27ac, 25, vl0028
- GSM7108232 right cardiac atrium, sinus rhythm, H3K27ac, 27, vl0031
- GSM7108233 left cardiac atrium, atrial fibrillation, H3K27ac, 28, vl0032
- GSM7108234 right cardiac atrium, atrial fibrillation, H3K27ac, 28, vl0033
- GSM7108235 left cardiac atrium, sinus rhythm, input, 12b, vl0034
- GSM7108236 right cardiac atrium, sinus rhythm, input, 12b, vl0035
- GSM7108237 left cardiac atrium, atrial fibrillation, input, 25, vl0036
- GSM7108238 right cardiac atrium, atrial fibrillation, input, 25, vl0037
- GSM7108239 left cardiac atrium, sinus rhythm, input, 27, vl0039
- GSM7108240 left cardiac atrium, atrial fibrillation, input, 28, vl0040
- GSM7108241 right cardiac atrium, atrial fibrillation, input, 28, vl0041
- GSM7108242 right cardiac atrium, atrial fibrillation, H3K27ac, 47, vl0211
- GSM7108243 left cardiac, atrium, atrial fibrillation, H3K27ac, 47, vl0212
- GSM7108244 left cardiac atrium, sinus rhythm, H3K27ac, 45, vl0213
- GSM7108245 right cardiac atrium, atrial fibrillation, H3K27ac, 2231, vl0214
- GSM7108246 left cardiac atrium, atrial fibrillation, H3K27ac, 31, vl0215
- GSM7108247 left cardiac atrium, sinus rhythm, H3K27ac, 20, vl0217
- GSM7108248 right cardiac atrium, sinus rhythm, H3K27ac, 33, vl0218
- GSM7108249 left cardiac atrium, atrial fibrillation, H3K4me3, 47, vl0220
- GSM7108250 left cardiac atrium, atrial fibrillation, H3K4me3, 31, vl0223
- GSM7108251 right cardiac atrium, atrial fibrillation, input, 47, vl0227
- GSM7108252 left cardiac atrium, atrial fibrillation, input, 47, vl0228
- GSM7108253 left cardiac atrium, sinus rhythm , iput, 45, vl0229
- GSM7108254 left cardiac atrium, atrial fibrillation, input, 31, vl0231
- GSM7108255 right cardiac atrium, sinus rhythm, input, 33, vl0234
- GSM7108256 left cardiac atrium, atrial fibrillation, H3K4me3, 2231, vl0248
- GSM7108257 left cardiac atrium, atrial fibrillation, H3K4me3, 313, vl0249
- GSM7108258 right cardiac atrium, atrial fibrillation, H3K4me3, 31, vl0250
- GSM7108259 right cardiac atrium, atrial fibrillation, H3K4me3, 313, vl0252
- GSM7108260 right cardiac atrium, sinus rhythm, H3K4me3, 20, vl0253
- GSM7108261 left cardiac atrium, atrial fibrillation, H3K27ac, 2231, vl0256
- GSM7108262 left cardiac atrium, atrial fibrillation, H3K27ac, 313, vl0257
- GSM7108263 right cardiac atrium, atrial fibrillation, H3K27ac, 31, vl0258
- GSM7108264 right cardiac atrium, atrial fibrillation, H3K27ac, 313, vl0260
- GSM7108265 right cardiac atrium, sinus rhytm, H3K27ac, 20, vl0261
- GSM7108266 left cardiac atrium, atrial fibrillation, input, 2231, vl0262
- GSM7108267 left cardiac atrium, atrial fibrillation, input, 313, vl0263
+ 12 more — browse all 52 samples with per-sample file links →
- GSE229482 ChIP-Seq analysis of H3K4me3 and H3K27ac histone marks without and with METTL8 knockdown 24 samples shares h3k27ac, h3k4me3, chip-seq
- GSE224357 H3K27ac ChIP-seq and RNA-seq of papillary thyroid carcinoma patient's tissues and paired normal tissues 12 samples shares h3k27ac, chip-seq, paired
- GSE275303 Identifying RARG fusions or PML-RARA binding genes or analysis the epigenetic changes (H3K27ac, H3K4me1, and H3K4me3) in hCD34+ cells overexpressing CPSF6::RARG and NUP98::RARG. 34 samples shares h3k27ac, h3k4me3
- GSE280574 mChIP-seq for high-throughput epigenomic profiling reveals a decoupling of H2A.Z and H3K4me3 in cancer 576 samples shares h3k4me3, chip-seq
- GSE239270 Investigate FOXA2, NKX2-1, CTCF and P300 cistrome and enhancer (H3K27ac and H3k4me1) reprogramming during NEPC transformation by ChIP-seq. 104 samples shares h3k27ac, chip-seq
- GSE310167 Embryonic stem cell factors DPPA2/4 amplify active H3K4me3-H2AK119ub chromatin domains in non-small cell lung cancer (ChIP-seq) 54 samples shares h3k4me3, chip-seq
- GSE290054 H3K4me3 instructs transcription at intergenic active regulatory elements [ChIP-seq] 35 samples shares h3k4me3, chip-seq
- GSE189215 H3K27ac and H3K27me3 ChIP-seq analysis for MDA-MB-468 cells treated with SAHA and sonidedgib 30 samples shares h3k27ac, chip-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.