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Role of DYRK1A in MPN

GSE228060 Homo sapiens Expression profiling by high throughput sequencing 9 samples Submitted 2025/03/03 Platform GPL11154
Summary
We aim to investigate the role of DYRK1A gene in MPN pathogenesis by DYRK inhibitor and genetic knockout
Published in
Chromothripsis-associated chromosome 21 amplification orchestrates transformation to blast-phase MPN through targetable overexpression of DYRK1A
Brierley CK, Yip BH, Orlando G et al. · Nature genetics 2025 · PMID 40490510 · doi:10.1038/s41588-025-02190-6
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Also filed as BioProject PRJNA947965 and SRA study SRP428937. Searching any of these in the dataset finder brings you back here.

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