Medullary cavity expansion is mediated by distinct cell populations during fetal bone development [bulk RNA-seq]
RNA-seq (gene expression) · mouse · 20 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 20 samples: 8 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Medullary cavity expansion is mediated by distinct cell populations during fetal bone developmentNature communications · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE228317_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA949253 and SRA study SRP429599. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 20 samples.
How we read this: 8 replicated groups read from 20 sample titles; they account for 20 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7118696 CD90negCD55neg, biol rep1 CD90negCD55neg, biol
- GSM7118697 CD90negCD55pos, biol rep1 CD90negCD55pos, biol
- GSM7118698 CD90posCD55neg, biol rep1 CD90posCD55neg, biol
- GSM7118699 CD90posCD55pos, biol rep1 CD90posCD55pos, biol
- GSM7118700 CD90negCD55neg, biol rep2 CD90negCD55neg, biol
- GSM7118701 CD90negCD55pos, biol rep2 CD90negCD55pos, biol
- GSM7118702 CD90posCD55neg, biol rep2 CD90posCD55neg, biol
- GSM7118703 CD90posCD55pos, biol rep2 CD90posCD55pos, biol
- GSM7118704 Tom-pos_EGFP-pos, biol rep1 Tom-pos_EGFP-pos, biol
- GSM7118705 Tom-pos_EGFP-neg, biol rep1 Tom-pos_EGFP-neg, biol
- GSM7118706 Tom-neg_EGFP-pos, biol rep1 Tom-neg_EGFP-pos, biol
- GSM7118707 Tom-neg_EGFP-neg, biol rep1 Tom-neg_EGFP-neg, biol
- GSM7118708 Tom-pos_EGFP-pos, biol rep2 Tom-pos_EGFP-pos, biol
- GSM7118709 Tom-pos_EGFP-neg, biol rep2 Tom-pos_EGFP-neg, biol
- GSM7118710 Tom-neg_EGFP-pos, biol rep2 Tom-neg_EGFP-pos, biol
- GSM7118711 Tom-neg_EGFP-neg, biol rep2 Tom-neg_EGFP-neg, biol
- GSM7118712 Tom-pos_EGFP-pos, biol rep3 Tom-pos_EGFP-pos, biol
- GSM7118713 Tom-pos_EGFP-neg, biol rep3 Tom-pos_EGFP-neg, biol
- GSM7118714 Tom-neg_EGFP-pos, biol rep3 Tom-neg_EGFP-pos, biol
- GSM7118715 Tom-neg_EGFP-neg, biol rep3 Tom-neg_EGFP-neg, biol
- GSE205410 Multiple subpopulations in medullary thymic epithelial cells are regulated by Aire with distinctive modes of gene regulations [bulkRNA-seq] 47 samples shares populations, medullary, distinct, rna-seq
- GSE303716 Nodal/Smad2 signaling sustains developmental pausing by repressing Pparg -mediated lipid metabolism [RNA-Seq] 24 samples shares mediated, rna-seq
- GSE293160 SKP1A-mediated degradation of PRC2 triggers activation of Polycomb-silenced gene [RNA-seq] 24 samples shares mediated, rna-seq
- GSE284808 Bulk RNAseq of sorted fibroblasts from a mouse model of stretch-mediated skin expansion 22 samples shares expansion, mediated
- GSE266145 Macrophage-mediated myelin recycling fuels brain cancer malignancy (scRNA-Seq) 22 samples shares mediated, rna-seq
- GSE269347 Daunorubicin-induced T cell remodeling facilitates a high antitumor response to PD-1 blockade therapy by promoting the expansion and effector function of CD8+ prolifeating T cells [scRNA-Seq] 16 samples shares expansion, rna-seq
- GSE286398 Lysine-specific demethylase 1 regulates hematopoietic stem cell expansion and myeloid cell differentiation [scRNA-seq] 13 samples shares expansion, rna-seq
- GSE315069 Smad4-p65 interactions drive BMP-mediated protection against inflammatory cell death [RNA-Seq] 12 samples shares mediated, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.