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Responses of human MAIT cells to CA7S

GSE228498 Homo sapiens Expression profiling by high throughput sequencing; Other 6 samples Submitted 2024/06/12 Platform GPL24676
Summary
To investigate the effect of cholic acid sulfate to MAIT cells, PBMCs were stimulated with 5-OP-RU and CA7S and scRNA sequencing was performed. Inflammatory genes were induced by 5-OP-RU, while wound healing related genes were inducesed by CA7S. This analysis showed that cholic acid sulfate may contributes to maintenance of MAIT cells.
Published in
Sulfated bile acid is a host-derived ligand for MAIT cells
Ito E, Inuki S, Izumi Y et al. · Science immunology 2024 · PMID 38277465 · doi:10.1126/sciimmunol.ade6924
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Also filed as BioProject PRJNA950061 and SRA study SRP429994. Searching any of these in the dataset finder brings you back here.

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