Amplified dosage of the NKX2-1 lineage transcription factor controls its oncogenic role in lung adenocarcinoma [ChIP-seq]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 25 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 25 samples: 22 distinct titles, 3 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Amplified dosage of the NKX2-1 lineage transcription factor controls its oncogenic role in lung adenocarcinomaMolecular cell · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE229540_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA954851 and SRA study SRP432306. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 25 sample titles: 22 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7165165 NCI-H2087 NKX2-1
- GSM7165166 NCI-H2087 EP300
- GSM7165167 NCI-H2087 H3K27ac
- GSM7165168 NCI-H2087 H3K4me1
- GSM7165169 NCI-H2087 Input Rep1
- GSM7165170 NCI-H2087 H3K4me3
- GSM7165171 NCI-H2087 RNAPolII
- GSM7165172 NCI-H2087 c-Jun
- GSM7165173 NCI-H2087 FOXA1
- GSM7165174 NCI-H2087 FOXA2
- GSM7165175 NCI-H2087 SOX2
- GSM7165176 NCI-H2087 CTCF
- GSM7165177 NCI-H2087 Input Rep2
- GSM7165178 NCI-H358 NKX2-1
- GSM7165179 NCI-H358 H3K27ac
- GSM7165180 NCI-H358 H3K4me1
- GSM7165181 NCI-H358 Input
- GSM7165182 NCI-H441 NKX2-1
- GSM7165183 NCI-H441 H3K27ac
- GSM7165184 NCI-H441 H3K4me1
- GSM7165185 NCI-H441 Input
- GSM7165186 HCC364 NKX2-1
- GSM7165187 HCC364 H3K27ac
- GSM7165188 HCC364 H3K4me1
- GSM7165189 HCC364 Input
- GSE293334 Allelic topological centering by transcription factors drives oncogenic multi-enhancer transcriptional regulation [ChIP-seq] 60 samples shares transcription, oncogenic, chip-seq
- GSE267597 AP-1 Mediates Oncogenic Transcription and Predicts Fatality in Lung Squamous Cell Carcinoma Patients [ChIP-seq] 36 samples shares transcription, oncogenic, chip-seq
- GSE284519 TRIM33 loss reduces Androgen Receptor transcriptional output and H2BK120 ubiquitination [ChIP-seq] 93 samples shares transcription, chip-seq
- GSE296190 Hypoxic regulation of chromatin and gene transcription [ChIP-seq] 84 samples shares transcription, chip-seq
- GSE335058 Evolutionary guided transcription factor design programs novel T cell states [ChIP-Seq] 66 samples shares transcription, chip-seq
- GSE296831 Epigenetic Context Defines the Transcriptional Activity of Canonical and Noncanonical NF-kappaB Signaling in Pancreatic Cancer [ChIP-Seq] 48 samples shares transcription, chip-seq
- GSE259248 ZBTB7A is a modulator of KDM5-driven transcriptional networks in basal breast cancer (ChIP-Seq) 36 samples shares transcription, chip-seq
- GSE300575 Cohesin acts as a transcriptional gatekeeper by restraining pause–release to promote processive elongation [ChIP-seq] 22 samples shares transcription, chip-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.