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Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity

GSE229591 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2024/08/07 Platform GPL17021
Summary
To investigate the role of IkE5 in Treg cell biology, we established IkE5-deficient Treg cells from Foxp3-Cre IkE5 floxed mice. We then performed gene expression profiling analysis using data obtained from bulk RNA-seq of wild-type and IkE5-deficient Treg cells.
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Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity
Ichiyama K, Long J, Kobayashi Y et al. · Immunity 2024 · PMID 39111316 · doi:10.1016/j.immuni.2024.07.010
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Also filed as BioProject PRJNA955112 and SRA study SRP434384. Searching any of these in the dataset finder brings you back here.

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