Distinct blood CD3+ CD14+ T Cell-Monocyte complexes harbor HIV and are dynamic, glucose-dependent and increased in individuals with glucose intolerance
RNA-seq (gene expression) · human · 3 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 3 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- CD3+ T-cell: CD14+ monocyte complexes are dynamic and increased with HIV and glucose intoleranceJournal of immunology (Baltimore, Md. : 1950) · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE230276_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA958179 and SRA study SRP433791. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 3 more — browse all 3 samples with per-sample file links →
- GSE336629 Integrated Transcriptomic Profiling of Rectal and Adipose HIV-1 Reservoirs Relative to Matched PBMCs in ART-Treated Individuals 14 samples shares hiv, individuals
- GSE274848 Association of smoking with neurocognition, inflammatory and myeloid cell activation profiles in people with HIV on ART 165 samples shares hiv
- GSE283710 RSK1 is an exploitable dependency in myeloid malignancies [CD34RNAseq] 90 samples shares cd3
- GSE290636 RNAseq analysis of blood specimens from ART-suppressed people with HIV prior to analytical treatment interruption 74 samples shares hiv
- GSE279719 Human CD14+ monocytes from early inflammatory arthritis patients before and after a 5day-and 30day-period of methotrexate treatment 72 samples shares cd14
- GSE230738 Dysfunctional effector memory CD8 T cells in the bronchoalveolar compartment of people living with HIV 71 samples shares hiv
- GSE262621 Gene expression profiling of HIV-associated diffuse large B-cell lymphomas from Malawi 70 samples shares hiv
- GSE339038 RNA-Seq of CD3+ T cells flow sorted from MLR assays with TNF/TNFR inhibitory compound combination treatments 64 samples shares cd3
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.