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Protective effect of Pien Tze Huang on colitis-associated colorectal cancer

GSE230302 Mus musculus Expression profiling by high throughput sequencing 20 samples 2025/01/01 GPL21273
Summary
The goal of this study is to compare the differentially expressed genes in colon tissue of Control and AOM/DSS induced colitis-associated cancer (CAC) mouse model with or without Pien Tze Huang (PZH) treatment. The AOM/DSS induced CAC mouse model were randomly divided into 2 groups: Model and Model + PZH groups (n=5 for each group). Control mice (n=5) were set as control. mice in Control and Model groups were intragastrically with double distilled water, while mice in PZH and Model + PZH groups were intragastrically with 250 mg/kg/d of PZH for 91 days. Then the colon tissues were used to identify differentially expressed genes among different groups.
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