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Chromatin conformation dynamics during CD4+ Tcell activation implicates autoimmune disease associated genes and regulatory elements (ATAC-Seq)

GSE230343 Homo sapiens Genome binding/occupancy profiling by high throughput sequencing 9 samples Submitted 2024/09/18 Platform GPL24676
Summary
We used ATAC-seq, RNA-seq, and HiC to create atlases of the regulatory elements to provide context to autoimmune disease associated variants from publically available Genome-wide association studies
Published in
Dynamic chromatin architecture identifies new autoimmune-associated enhancers for IL2 and novel genes regulating CD4+ T cell activation
Pahl MC, Sharma P, Thomas RM et al. · eLife 2024 · PMID 39302339 · doi:10.7554/eLife.96852
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Also filed as BioProject PRJNA960640 and SRA study SRP433910. Searching any of these in the dataset finder brings you back here.

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