Chromatin topology dynamics of dexamethasone-treated trabecular meshwork identifies 78 causal genes for intraocular pressure and primary open angle glaucoma [CUT&Run]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 30 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 30 samples: 24 distinct titles, 3 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Chromatin dynamics identifies 78 genes at loci associated with elevated intraocular pressure and primary open-angle glaucomabioRxiv : the preprint server for biology · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE301512_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1285378 and SRA study SRP597777. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 30 sample titles: 24 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9084510 Resource CUT&Run TM62 CTCF
- GSM9084511 Resource CUT&Run TM62 H3K4me1
- GSM9084512 Resource CUT&Run TM62 H3K4me2
- GSM9084513 Resource CUT&Run TM62 H3K4me3
- GSM9084514 Resource CUT&Run TM62 H3K9me3
- GSM9084515 Resource CUT&Run TM62 H3K27Ac (Abcam)
- GSM9084516 Resource CUT&Run TM62 H3K27Ac (Activemotif)
- GSM9084517 Resource CUT&Run TM62 H3K27me3
- GSM9084518 Resource CUT&Run TM62 H3K36me3
- GSM9084519 Resource CUT&Run TM62 IgG
- GSM9084520 Resource CUT&Run TM71 CTCF
- GSM9084521 Resource CUT&Run TM71 H3K4me1
- GSM9084522 Resource CUT&Run TM71 H3K4me2
- GSM9084523 Resource CUT&Run TM71 H3K4me3
- GSM9084524 Resource CUT&Run TM71 H3K9me3
- GSM9084525 Resource CUT&Run TM71 H3K27Ac (Abcam)
- GSM9084526 Resource CUT&Run TM71 H3K27Ac (Activemotif)
- GSM9084527 Resource CUT&Run TM71 H3K27me3
- GSM9084528 Resource CUT&Run TM71 H3K36me3
- GSM9084529 Resource CUT&Run TM71 IgG
- GSM9084530 Resource CUT&Run TM83 CTCF
- GSM9084531 Resource CUT&Run TM83 H3K4me1
- GSM9084532 Resource CUT&Run TM83 H3K4me2
- GSM9084533 Resource CUT&Run TM83 H3K4me3
- GSM9084534 Resource CUT&Run TM83 H3K9me3
- GSM9084535 Resource CUT&Run TM83 H3K27Ac (Abcam)
- GSM9084536 Resource CUT&Run TM83 H3K27Ac (Activemotif)
- GSM9084537 Resource CUT&Run TM83 H3K27me3
- GSM9084538 Resource CUT&Run TM83 H3K36me3
- GSM9084539 Resource CUT&Run TM83 IgG
- GSE301516 Chromatin topology dynamics of dexamethasone-treated trabecular meshwork identifies 78 causal genes for intraocular pressure and primary open angle glaucoma [ATAC] 12 samples shares dexamethasone-treated, intraocular, trabecular, identifies, chromatin, topology, dynamics
- GSE327821 Single-molecule, single-cell profiling of linked chromatin states [Single_cell_CoCUT&Tag] 200 samples shares cut, chromatin
- GSE287902 BPTF regulstes androgen receptor activity by enhancing chromatin accessibility and stabilizing the AR-FOXA1 interaction [Cut&Run] 40 samples shares cut, chromatin
- GSE327819 Single-molecule, single-cell profiling of linked chromatin states [Bulk_CoCUT&Tag] 35 samples shares cut, chromatin
- GSE310696 Systematic Benchmarking of CUT&Tag Improves the Reliability and Reproducibility of Chromatin Analysis [Crosslinking] 31 samples shares cut, chromatin
- GSE278910 Pooled CRISPR screens with joint single-nucleus chromatin accessibility and transcriptome profiling [CUT&RUN] 30 samples shares cut, chromatin
- GSE268035 STAG2 Mutations Reshape the Cohesin-Structured Spatial Chromatin Architecture to Drive Gene Regulation in Acute myeloid Leukemia 541 samples shares cut, chromatin
- GSE270125 Divergent medulloblastoma chromatin states disclose KDM2B as a selective dependency [CUT&Run] 169 samples shares cut, chromatin
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.