Bulk RNA-seq of ILC2, Tconv, Th2, Treg Gata3hi and Treg Gatalo from the lungs of IL-33 treated mice
RNA-seq (gene expression) · mouse · 22 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 22 samples: 5 conditions, mostly with about 5 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Cross-talk between ILC2 and Gata3(high) T(regs) locally constrains adaptive type 2 immunityScience immunology · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE230597_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA961819 and SRA study SRP434466. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 22 samples.
How we read this: 5 replicated groups read from 22 sample titles; they account for 22 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7229636 ILC2 cells, rep4 ILC2 cells,
- GSM7229637 ILC2 cells, rep5 ILC2 cells,
- GSM7229638 Tconv cells, rep1 Tconv cells,
- GSM7229639 Tconv cells, rep2 Tconv cells,
- GSM7229640 Tconv cells, rep3 Tconv cells,
- GSM7229641 Tconv cells, rep4 Tconv cells,
- GSM7229642 Tconv cells, rep5 Tconv cells,
- GSM7229643 Th2 cells, rep1 Th2 cells,
- GSM7229644 Th2 cells, rep2 Th2 cells,
- GSM7229645 Th2 cells, rep3 Th2 cells,
- GSM7229646 Th2 cells, rep4 Th2 cells,
- GSM7229647 Th2 cells, rep5 Th2 cells,
- GSM7229648 TregGata3hi cells, rep1 TregGata3hi cells,
- GSM7229649 TregGata3hi cells, rep2 TregGata3hi cells,
- GSM7229650 TregGata3hi cells, rep3 TregGata3hi cells,
- GSM7229651 TregGata3hi cells, rep4 TregGata3hi cells,
- GSM7229652 TregGata3hi cells, rep5 TregGata3hi cells,
- GSM7229653 TregGata3lo cells, rep1 TregGata3lo cells,
- GSM7229654 TregGata3lo cells, rep2 TregGata3lo cells,
- GSM7229655 TregGata3lo cells, rep3 TregGata3lo cells,
- GSM7229656 TregGata3lo cells, rep4 TregGata3lo cells,
- GSM7229657 TregGata3lo cells, rep5 TregGata3lo cells,
- GSE248386 ILC2 regulate a Pi16+ fibroblast progenitor niche in the pancreas (acute pancreatitis scRNA-seq) 10 samples shares ilc2, rna-seq
- GSE325329 Transcriptomic profiling of macrophages that phagocytosed apoptotic Treg or conventional CD4⁺ T (Tconv) cells under different polarization conditions [RNA-Seq] 28 samples shares rna-seq, tconv
- GSE264105 Plate-based scRNA-seq of plasma-positive microglia and plasma-negative microglia in young mice 1111 samples shares rna-seq
- GSE314943 Single-cell multiomics uncovers an endothelial mechanosensitive PIEZO1-IL-33 axis driving pulmonary fibrosis 18 samples shares il-33
- GSE277789 Spatiotemporal and genetic cell lineage tracing of endodermal organogenesis at single-cell resolution [Smart-seq3-RNA-seq-add] 830 samples shares rna-seq
- GSE326100 scRNA-seq of mouse cochlea organoid cells 768 samples shares rna-seq
- GSE311449 Single cell RNA-seq of mouse brain vascular cells with Smart-seq2 method 391 samples shares rna-seq
- GSE319614 Bulk RNA-seq transcriptome profiling of hippocampus across 17 autism spectrum disorder mouse models 269 samples shares rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.