Sepsis-secreted G6PD supports guanine generation and Histone H3K27 demethylation to drive inflammatory macrophages

Direct links to NCBI, no account and no request form: the whole study as GSE230648_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 9 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA962065 and SRA study SRP434622. Searching any of these in the dataset finder brings you back here.

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• GSE319035 P21+TREM2+-Senescent Macrophages Fuel Inflammaging and Metabolic Dysfunction-Associated Steatotic Liver Disease [NAFLD_time_course] 77 samples
• GSE321707 Characterization of TLR signaling in Ticam2-/- macrophages 30 samples
• GSE343043 Disease context dictates the cellular targets of IL-17 in inflammatory skin disease 29 samples
• GSE341985 Diseaase context dictates the cellular targets of IL-17 in inflammatory skin disease [2] 27 samples
• GSE337190 CAR-NKT cells induce low cytokine release syndrome by targeting hyperinflammatory macrophages with mitigation from GM-SCF inhibition. 24 samples
• GSE338763 Inflammatory Neuropathy in Mouse and Primate Models of Colorectal Cancer 24 samples
• GSE304706 Persistent ER stress in macrophages fuels age-related inflammation and vulnerability to infection 8 samples
• GSE281001 The C3-C3aR axis modulates trained immunity in alveolar macrophages 8 samples

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