The role of MEIOC at the transition from mitosis to meiosis during mammalian spermatogenesis
RNA-seq (gene expression) · mouse · 11 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 11 samples: 4 × preleptotene-enriched testes, wild-type, vs 3 × preleptotene-enriched testes, Meioc KO,Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Destabilization of mRNAs enhances competence to initiate meiosis in mouse spermatogenic cellsDevelopment (Cambridge, England) · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE230747_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA962497 and SRA study SRP434842. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 7 samples.
How we read this: 2 replicated groups read from 11 sample titles; they account for 7 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7233582 preleptotene-enriched testes, wild-type, biological replicate 1 preleptotene-enriched t…
- GSM7233583 preleptotene-enriched testes, wild-type, biological replicate 2 preleptotene-enriched t…
- GSM7233584 preleptotene-enriched testes, wild-type, biological replicate 3 preleptotene-enriched t…
- GSM7233585 preleptotene-enriched testes, wild-type, biological replicate 4 preleptotene-enriched t…
- GSM7233586 preleptotene-enriched testes, Meioc KO, biological replicate 1 preleptotene-enriched t…
- GSM7233587 preleptotene-enriched testes, Meioc KO, biological replicate 2 preleptotene-enriched t…
- GSM7233588 preleptotene-enriched testes, Meioc KO, biological replicate 3 preleptotene-enriched t…
- GSM7233604 wild-type P15 testes, biological replicate 1, scRNAseq
- GSM7233605 wild-type P15 testes, biological replicate 2, scRNAseq
- GSM7233606 Meioc KO P15 testes, biological replicate 1, scRNAseq
- GSM7233607 Meioc KO P15 testes, biological replicate 2, scRNAseq
- GSE196779 Nucleolar migration regulates meiotic sex chromosome inactivation via phase separation during mammalian spermatogenesis 30 samples shares spermatogenesis, mammalian
- GSE264153 TATA-binding Associated Factors have distinct roles during early mammalian development 57 samples shares mammalian
- GSE274544 Single cell profiling reveals three endothelial to hematopoietic transitions with divergent isoform expression landscapes [scRNA-Seq] 1494 samples shares transition
- GSE248194 Characterizing dynamics and lineage of bihormonal cell in mammalian pancreatic islets [Smart-seq3xpress] 1430 samples shares mammalian
- GSE289641 Noncanonical PRC2 chromatin association reveals a key role of EZHIP in intergenerational epigenetic memory transition [RNA-Seq] 68 samples shares transition
- GSE288245 Long-term post-ovariectomy mouse model recapitulates hypothalamic transcriptomic changes observed during the menopausal transition in women 33 samples shares transition
- GSE241388 Transcriptome analysis of oocytes and early embryos to demonstrate trancriptional regulation during mouse oocyte-to-embryo transition 32 samples shares transition
- GSE259426 miR-203 facilitates timely cell fate transitions via epigenetic modulation during early embryogenesis (RNA-Seq) 27 samples shares transition
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.