NUDT21 alters glioma migration through differential alternative polyadenylation of LAMC1
RNA-seq (gene expression) · human · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 12 samples: 3 × LN229 Scramble vs 3 × LN229 shNUDT21 vs 3 × U251 Scramble vs 3 × U251 shNUDT21Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE230769_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA962545 and SRA study SRP434887. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7234027 LN229 Scramble 1 LN229 Scramble
- GSM7234028 LN229 Scramble 2 LN229 Scramble
- GSM7234029 LN229 Scramble 3 LN229 Scramble
- GSM7234030 LN229 shNUDT21 1 LN229 shNUDT21
- GSM7234031 LN229 shNUDT21 2 LN229 shNUDT21
- GSM7234032 LN229 shNUDT21 3 LN229 shNUDT21
- GSM7234033 U251 Scramble 1 U251 Scramble
- GSM7234034 U251 Scramble 2 U251 Scramble
- GSM7234035 U251 Scramble 3 U251 Scramble
- GSM7234036 U251 shNUDT21 1 U251 shNUDT21
- GSM7234037 U251 shNUDT21 2 U251 shNUDT21
- GSM7234038 U251 shNUDT21 3 U251 shNUDT21
- GSE287072 Alternative splicing and differential gene expression during changes in endometrial receptivity in patients with recurrent implantation failure 73 samples shares differential, alternative
- GSE304550 ALS-Associated TDP-43 Dysfunction Compromises UPF1-Dependent mRNA Metabolism Pathways Including Alternative Polyadenylation and 3’UTR Length 16 samples shares polyadenylation, alternative
- GSE291390 Single-cell landscape and regulation of alternative polyadenylation in the brain 15 samples shares polyadenylation, alternative
- GSE269596 Multiplexed single-cell characterization of alternative polyadenylation regulators (scRNA-Seq) 12 samples shares polyadenylation, alternative
- GSE269600 Multiplexed single-cell characterization of alternative polyadenylation regulators 52 samples shares polyadenylation, alternative
- GSE252392 U1 snRNP regulates alternative promoter activity by inhibiting premature polyadenylation 47 samples shares polyadenylation, alternative
- GSE313109 HIV-1 Infection Regulates Gene Expression by Altering Alternative Polyadenylation Through CPSF6 and CPSF5 Delocalization 28 samples shares polyadenylation, alternative
- GSE210746 Characterization of 3′UTRCES-mediated alternative polyadenylation (APA) engineering in prostate cancer and 293FT cells 15 samples shares polyadenylation, alternative
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.