GEO series
Single-cell transcriptomic analysis of human skin organoids during folliculogenesis
GSE231607
Homo sapiens
Expression profiling by high throughput sequencing
10 samples
2024/05/01
GPL18573GPL24676
Summary
In this study, we defined a differentiation approach for guiding human pluripotent stem cells in to complex hair-bearing skin tissue, known as skin organoids. The primary goal of this single-cell RNA-sequencing analysis was to define the cellular composition of skin organoids before, during, and after the process of hair folliculogenesis. The secondary goal was to determine whether skin organoids generated using different cell lines (WA25 hESCs and DSP-GFP hiPSCs) contain similar cell types and accurately reflect features of developing fetal skin tissue.
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Paper (PMID 39415002) ↗
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