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Long term effects of CCR2+ myeloid cell depletion on islet cell populations identified by scRNA-seq

GSE232461 Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2024/08/31 Platform GPL30172
Summary
Pancreatic islets were isolated from 1 month and 6 months old CCR2-DTR+/- and wild type mice, previously treated with diphtheria toxin to transiently deplete CCR2+ myeloid cells during the first 10 days of life.
Published in
Disruption of perinatal myeloid niches impacts the aging clock of pancreatic β cells
O'Sell J, Cirulli V, Pardike S et al. · iScience 2024 · PMID 39262794 · doi:10.1016/j.isci.2024.110644
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Also filed as BioProject PRJNA972119 and SRA study SRP437495. Searching any of these in the dataset finder brings you back here.

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