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Increased YAP transcriptional activity in in male murine steroidogenic zG adrenocortical cells

GSE233263 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2024/12/30 Platform GPL19057
Summary
To specifically evaluate the effect of an increase of the transcriptional activity of YAP in mice adrenal gland we generated a mouse mode expressing a constitutively active form of human YAP (YAP5SA) in aldosterone-producing zG cells. RNAseq analysis on whole adrenal glands were performed on one month male mice
Published in
Hippo Signaling Is Essential for the Maintenance of Zona Glomerulosa Cell Fate in the Murine Adrenal Cortex
Abou Nader N, Jakuc N, Meinsohn MC et al. · Endocrinology 2025 · PMID 40233139 · doi:10.1210/endocr/bqaf077
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Also filed as BioProject PRJNA975584 and SRA study SRP439178. Searching any of these in the dataset finder brings you back here.

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