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Single cell transcriptome atlas revealed the feature of contemporary ZIKA virus induced microcephaly in mice

GSE233624 Mus musculus Expression profiling by high throughput sequencing 3 samples Submitted 2026/06/01 Platform GPL24247
Summary
Zika virus (ZIKV), a mosquito-borne flavivirus, has imposed tremendous global threat to human health and was declared as a public health emergency of international concern by the World Health Organization in 2016. However, the pathogenic mechanism of ZIKV still lacks sufficient understanding. In recent years, the development of single-cell sequencing technology has provided a more precise approach for exploring disease mechanisms. Therefore, in this study, we depicted a high-resolution transcriptomic landscape and functional changes of brain immune and neural cells during disease progression of ZIKV, which will facilitate a better understanding of the underlying pathogenesis of ZIKV-induced microcephaly.
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Direct links to NCBI, no account and no request form: the whole study as GSE233624_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 3 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA976927 and SRA study SRP439898. Searching any of these in the dataset finder brings you back here.

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