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Identifying the role of FOXM1 in human primary renal tubular epithelials using bulk RNA-seq and Cut&Run to understand its role in acute kidney injury and repair [RNA-seq]

GSE234443 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2024/07/12 Platform GPL24676
Summary
In this dataset, we study the role of FOXM1 in human primary renal tubular epithelial cells (hRPTECs) by first performing Foxm1 knockdown with an siRNA approach and then performing bulk RNA sequencing. We also sought to identify FOXM1 binding sites on hRPTECs using Cut&Run. These studies will help better understand the role of Foxm1 in acute kidney injury and repair.
Published in
Injury-induced Foxm1 expression in the mouse kidney drives epithelial proliferation by a cyclin F-dependent mechanism
Noonan ML, Muto Y, Yoshimura Y et al. · JCI insight 2024 · PMID 38916959 · doi:10.1172/jci.insight.175416
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Also filed as BioProject PRJNA981450 and SRA study SRP441800. Searching any of these in the dataset finder brings you back here.

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