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Single-cell gene expression profiles of head-and-neck squamous cell carcinoma from a cohort of patients

GSE234933 Homo sapiens Expression profiling by high throughput sequencing 52 samples Submitted 2023/07/24 Platform GPL18573
Summary
This scRNA dataset was aimed to provide comprehensive profiling of head-and-neck tumor tissues, in order to explore and elucidate patterns of molecular and cellular interactions between the tumor cells and their patient-specific microenvironments. No specific enrichment of a particular cell types were performed to allow comprehensive representation of all cell types. To allow between-patient comparisons, relatively large number of samples from patients with a wide range of patients characteristics and tissue source (primary, recurrence and metastasis) were chosen. The dataset was intended for multiple investigations on specific pathways and cell types of tumor microenvironments.
Published in
CXCL9:SPP1 macrophage polarity identifies a network of cellular programs that control human cancers
Bill R, Wirapati P, Messemaker M et al. · Science (New York, N.Y.) 2023 · PMID 37535729 · doi:10.1126/science.ade2292
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Direct links to NCBI, no account and no request form: the whole study as GSE234933_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 52 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA983770. Searching any of these in the dataset finder brings you back here.

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