GEO series

Expression data from osteocytes in virgin,lactating and post lactation mice

GSE23496 Mus musculus (mouse) Expression microarray 9 samples Submitted 2011/12/31 Platform GPL1261

At a glance

Expression microarray · mouse · 9 samples

What it is: Expression microarrayGene activity read on a chip (the older technology that RNA-seq replaced).
Organism: Mus musculus (mouse)
Samples: 9 samples
Data you can get: A processed expression table (series matrix) and the array files, from NCBI.

Summary (written by the submitters)

We have previously shown that during lactation, osteocytes directly remodel their perilacunar and pericanalicular matrix, thereby mobilizing calcium and contributing to maternal bone loss. To identify genes potentially responsible for perilacunar remodeling, microarray analysis was performed on osteocytes from CD-1 virgin and lactating mice and mice sacrificed on day 7 post weaning. By comparing how gene expression changes in osteocytes among virgin, lactation and post lactation, the goal is to identify the genes osteocytes use to remodel their perilacunar matrix

This dataset

Open GSE23496 in finder → Find more mouse microarray datasets →

Download · which file do I need?

Direct links to NCBI, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.

1 · Just have a look

Processed table

The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.

Series matrix ↓

2 · Re-analyse it

Supplementary files

The count tables and other files the authors uploaded. Take only the samples you need.

All supplementary files ↗

3 · The original raw files

Whole study · RAW.tar

Everything the authors deposited as one archive (GSE23496_RAW.tar), including the raw array or instrument files. Can be large; the picker in step 2 takes just the samples you need.

Whole study · RAW.tar ↓

What the files usually look like: For arrays the series matrix is normally the normalised expression table you want; the raw array files (CEL and similar) are in the RAW.tar.

Also filed as BioProject PRJNA131005. Searching any of these in the dataset finder brings you back here.

NCBI GEO page ↗ Paper (PMID 22308018) ↗

Samples in this study

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+ 9 more — browse all 9 samples with per-sample file links →

Datasets on a similar topic

GSE217677 Maternal dietary fat during lactation shapes single nucleus transcriptomic profile of postnatal offspring hypothalamus in a sexually dimorphic manner in mice 8 samples shares lactation, post
GSE272881 Organellar responses to lactation-induced stress impact the fate of post-partum mammary glands. 24 samples shares lactation, post
GSE20402 Mouse mammary epithelial cell subpopulations from pregnant and virgin mice 14 samples shares virgin
GSE268503 Gene expression profile at single cell level of intestinal lamina propria cells from nulliparous mice and lactating mice 2 samples shares lactating
GSE247929 Growth of the maternal intestine during pregnancy and lactation 107 samples shares lactation
GSE247926 Growth of the maternal intestine during pregnancy and lactation [gut sections] 54 samples shares lactation
GSE248882 Brain-Derived CCN3 Is An Osteoanabolic Hormone That Sustains Bone in Lactating Females 44 samples shares lactating
GSE270276 A long-lasting prolactin to combat lactation insufficiency 36 samples shares lactation

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