Transcriptomic analysis of 30dpp ovaries and 35dpp testes exposed to the cocktails of pharmaceuticals ibuprofen (IBU), 2hydroxyIBU (2hIBU), diclofenac (DCF) and 17a ethinyl-estradiol (EE2) in mice
RNA-seq (gene expression) · mouse · 54 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 54 samples: 54 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE235586_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA986506 and SRA study SRP445381. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 54 sample titles: 54 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7505885 MF1_P_CtrlA_S55 Male F1 Control sample A
- GSM7505886 MF1_P_CtrlB_S56 Male F1 Control sample B
- GSM7505887 MF1_P_CtrlC_S57 Male F1 Control sample C
- GSM7505888 MF1_P_D1A_S58 Male F1 Dose 1 sample A
- GSM7505889 MF1_P_D1B_S59 Male F1 Dose 1 sample B
- GSM7505890 MF1_P_D1C_S60 Male F1 Dose 1 sample C
- GSM7505891 MF1_P_D2A_S61 Male F1 Dose 2 sample A
- GSM7505892 MF1_P_D2B_S62 Male F1 Dose 2 sample B
- GSM7505893 MF1_P_D2C_S63 Male F1 Dose 2 sample C
- GSM7505894 MF2_P_CC_A_S64 Male F2 (MaleCTL x FemaleCTL) sample A
- GSM7505895 MF2_P_CC_B_S65 Male F2 (MaleCTL x FemaleCTL) sample B
- GSM7505896 MF2_P_CC_C_S66 Male F2 (MaleCTL x FemaleCTL) sample C
- GSM7505897 MF2_P_CD1_A_S67 Male F2 (MaleCTL x FemaleDose1) sample A
- GSM7505898 MF2_P_CD1_B_S68 Male F2 (MaleCTL x FemaleDose1) sample B
- GSM7505899 MF2_P_CD1_C_S69 Male F2 (MaleCTL x FemaleDose1) sample C
- GSM7505900 MF2_P_CD2_A_S70 Male F2 (MaleCTL x FemaleDose2) sample A
- GSM7505901 MF2_P_CD2_B_S71 Male F2 (MaleCTL x FemaleDose2) sample B
- GSM7505902 MF2_P_CD2_C_S72 Male F2 (MaleCTL x FemaleDose2) sample C
- GSM7505903 MF2_P_D1C_A_S73 Male F2 (MaleDose1 x FemaleCTL) sample A
- GSM7505904 MF2_P_D1C_B_S74 Male F2 (MaleDose1 x FemaleCTL) sample B
- GSM7505905 MF2_P_D1C_C_S75 Male F2 (MaleDose1 x FemaleCTL) sample C
- GSM7505906 MF2_P_D2C_A_S76 Male F2 (MaleDose2 x FemaleCTL) sample A
- GSM7505907 MF2_P_D2C_B_S77 Male F2 (MaleDose2 x FemaleCTL) sample B
- GSM7505908 MF2_P_D2C_C_S78 Male F2 (MaleDose2 x FemaleCTL) sample C
- GSM7505909 MF2_P_D2D2_A_S79 Male F2 (MaleDose2 x FemaleDose2) sample A
- GSM7505910 MF2_P_D2D2_B_S80 Male F2 (MaleDose2 x FemaleDose2) sample B
- GSM7505911 MF2_P_D2D2_C_S81 Male F2 (MaleDose2 x FemaleDose2) sample C
- GSM7505912 FF1_P_CtrlA_S1 Female F1 Control sample A
- GSM7505913 FF1_P_CtrlB_S2 Female F1 Control sample B
- GSM7505914 FF1_P_CtrlC_S3 Female F1 Control sample C
- GSM7505915 FF1_P_D1A_S4 Female F1 Dose 1 sample A
- GSM7505916 FF1_P_D1B_S5 Female F1 Dose 1 sample B
- GSM7505917 FF1_P_D1C_S6 Female F1 Dose 1 sample C
- GSM7505918 FF1_P_D2A_S7 Female F1 Dose 2 sample A
- GSM7505919 FF1_P_D2B_S8 Female F1 Dose 2 sample B
- GSM7505920 FF1_P_D2C_S9 Female F1 Dose 2 sample C
- GSM7505921 FF2_P_CC_A_S10 Female F2 (MaleCTL x FemaleCTL) sample A
- GSM7505922 FF2_P_CC_B_S11 Female F2 (MaleCTL x FemaleCTL) sample B
- GSM7505923 FF2_P_CC_C_S12 Female F2 (MaleCTL x FemaleCTL) sample C
- GSM7505924 FF2_P_CD1_A_S13 Female F2 (MaleCTL x FemaleDose1) sample A
+ 14 more — browse all 54 samples with per-sample file links →
- GSE229916 Pericytes and perivascular fibroblasts contribute to central nervous system fibrosis in a region dependent manner 832 samples shares ibu
- GSE309251 Western diet-induced MASH in PWK/PhJ mice identifies disruptions in amino acid and sphingolipid metabolism contributing to cardiac dysfunction 347 samples shares ibu
- GSE301899 mTOR signaling contributes to system-driven rhythmic gene expression in mouse liver 282 samples shares ibu
- GSE309042 S100A4-lineage Cells Contribute Modesty to Angiotensin II-mediated Thoracic Aortic Aneurysms Through Angiotensin II Type 1a Receptor in Mice 86 samples shares ibu
- GSE262418 Gpr37 contributes to inflammation-induced GI dysmotility by regulating enteric reactive gliosis. 75 samples shares ibu
- GSE279353 Characterization of POP mixture redistribution and identification of their molecular signature in xenografted fat mice 54 samples shares ibu
- GSE279731 The contribution of foam cells to angiogenesis and inflammation after spinal cord injury 48 samples shares ibu
- GSE334405 cGAS-mediated IFN-I signaling contributes to disease progression in drug-refractory epilepsy 44 samples shares ibu
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.