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Genetic and Environmental interactions contribute to immune variation in rewilded mice

GSE236347 Mus musculus Expression profiling by high throughput sequencing 14 samples 2024/04/29 GPL19057
Summary
The relative and synergistic contributions of genetics and environment to inter-individual immune response variation remain unclear, despite its implications for understanding both evolutionary biology and medicine. We used single cell RNA sequencing (scRNA-seq) to quantify the interactive effects of genotype and environment on immune traits by investigating three inbred mouse sttrain rewilded in an outdoor enclosure and infected with the parasite, Trichuris muris
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