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Genetic variation modulates aberrant DNA hypomethylation in naïve pluripotent stem cells.

GSE267262 Mus musculus Expression profiling by high throughput sequencing 12 samples 2025/05/22 GPL24247
Summary
We observed markedly different DNA methylation chances in response to MAP kinase inhibition between 129 and B6J mESCs. We reasoned that these differences at least in part are driven by the differential expression of DNA methylation regulators and conducted RNA sequencing experiments.
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