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Epigenetic and transcriptional alterations with Kmt2c and Kmt2d loss in urothelial cells

GSE236370 Mus musculus Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other 40 samples 2024/08/09 GPL17021
Summary
KMT2C and KMT2D are two of the most frequently mutated genes in bladder cancer and in histologically normal urothelium. In this study, we developed mouse models to investigate the molecular mechanism of Kmt2c/d loss in urothelial tumorigenesis.
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