Convergence of aging- and rejuvenation-related epigenetic alterations on PRC2 targets
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 39 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 39 samples: 11 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Convergence of aging- and rejuvenation-related epigenetic alterations on PRC2 targetsMolecular systems biology · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE289856_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1225190 and SRA study SRP436016. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 39 samples.
How we read this: 11 replicated groups read from 39 sample titles; they account for 39 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7295273 Young_Skin_Control_1 Young_Skin_Control
- GSM7295274 Young_Skin_Control_3 Young_Skin_Control
- GSM7295275 Young_Skin_Control_4 Young_Skin_Control
- GSM7295276 Old_Skin_Control_5760 Old_Skin_Control
- GSM7295277 Old_Skin_Control_5761 Old_Skin_Control
- GSM7295278 Old_Skin_Control_5762 Old_Skin_Control
- GSM7295279 Old_Skin_Control_5764 Old_Skin_Control
- GSM7295280 Old_Skin_Dox_253 Old_Skin_Dox
- GSM7295281 Old_Skin_Dox_284 Old_Skin_Dox
- GSM7295282 Old_Skin_Dox_285 Old_Skin_Dox
- GSM7295283 Old_Skin_Dox_288 Old_Skin_Dox
- GSM7295284 Old_Skin_Dox_904 Old_Skin_Dox
- GSM8770163 Young tail epidermis, H3K27me3, biol rep 1 Young tail epidermis, H…
- GSM8770165 Young tail epidermis, H3K27me3, biol rep 2 Young tail epidermis, H…
- GSM8770166 Old tail epidermis, H3K27me3, biol rep 1 Old tail epidermis, H3K…
- GSM8770167 Old tail epidermis, H3K27me3, biol rep 2 Old tail epidermis, H3K…
- GSM8770168 Old tail epidermis, H3K27me3, biol rep 3 Old tail epidermis, H3K…
- GSM8770169 Young tail epidermis, INPUT, biol rep 1 Young tail epidermis, I…
- GSM8770170 Young tail epidermis, INPUT, biol rep 2 Young tail epidermis, I…
- GSM8770171 Young tail epidermis, INPUT, biol rep 3 Young tail epidermis, I…
- GSM8770172 Old tail epidermis, INPUT, biol rep 1 Old tail epidermis, INP…
- GSM8770173 Old tail epidermis, INPUT, biol rep 2 Old tail epidermis, INP…
- GSM8770174 Old tail epidermis, INPUT, biol rep 3 Old tail epidermis, INP…
- GSM8800284 Young tail epidermis, biol rep 1 Young tail epidermis, b…
- GSM8800285 Young tail epidermis, biol rep 2 Young tail epidermis, b…
- GSM8800286 Young tail epidermis, biol rep 3 Young tail epidermis, b…
- GSM8800287 Young tail epidermis, biol rep 4 Young tail epidermis, b…
- GSM8800288 Young tail epidermis, biol rep 5 Young tail epidermis, b…
- GSM8800289 Old tail epidermis, biol rep 1 Old tail epidermis, biol
- GSM8800290 Old tail epidermis, biol rep 2 Old tail epidermis, biol
- GSM8800291 Old tail epidermis, biol rep 3 Old tail epidermis, biol
- GSM8800292 Old tail epidermis, biol rep 4 Old tail epidermis, biol
- GSM8800293 Old tail epidermis, biol rep 5 Old tail epidermis, biol
- GSM9386519 Young tail epidermis, H3K9me2, biol rep 1 Young tail epidermis, H…
- GSM9386520 Young tail epidermis, H3K9me2, biol rep 2 Young tail epidermis, H…
- GSM9386521 Young tail epidermis, H3K9me2, biol rep 3 Young tail epidermis, H…
- GSM9386522 Old tail epidermis, H3K9me2, biol rep 1 Old tail epidermis, H3K…
- GSM9386523 Old tail epidermis, H3K9me2, biol rep 2 Old tail epidermis, H3K…
- GSM9386524 Old tail epidermis, H3K9me2, biol rep 3 Old tail epidermis, H3K…
- GSE288574 Convergence of aging- and rejuvenation-related epigenetic alterations on PRC2 targets [ChIP-Seq] 17 samples shares prc2, rejuvenation-related, convergence, alterations, epigenetic, targets, aging
- GSE299940 Cortical Alterations in H3K27ac Regulation in Gene Expression Coincide Associated with Cognitive Decline and Affective Behavior in Mice During Aging: Genome-wide Epigenetic Analysis 12 samples shares alterations, epigenetic, aging
- GSE272603 DNA glycosylases Ogg1 and Mutyh mediate gene expression of PRC2 targets important for memory formation 128 samples shares prc2, targets
- GSE289642 Noncanonical PRC2 chromatin association reveals a key role of EZHIP in intergenerational epigenetic memory transition [ChIP-Seq, Cut & Run] 107 samples shares prc2, epigenetic
- GSE272601 DNA glycosylases Ogg1 and Mutyh mediate gene expression of PRC2 targets important for memory formation (ChIP-Seq) 96 samples shares prc2, targets
- GSE289641 Noncanonical PRC2 chromatin association reveals a key role of EZHIP in intergenerational epigenetic memory transition [RNA-Seq] 68 samples shares prc2, epigenetic
- GSE270581 Chromatin distribution alterations of histone modifacations and PRC2 complex caused by Rack7 deletion in primary astrocyte [ChIP-Seq] 24 samples shares prc2, alterations
- GSE272602 DNA glycosylases Ogg1 and Mutyh mediate gene expression of PRC2 targets important for memory formation (RNA-Seq) 24 samples shares prc2, targets
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.