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Single nucleus transcriptomic analysis of osimertinib-induced cardiac dysfunction in the mouse heart

GSE236762 Mus musculus Expression profiling by high throughput sequencing 8 samples Submitted 2026/01/09 Platform GPL24247
Summary
We performed single nuclei RNA sequencing (snRNA-seq) analysis of mouse left ventricular tissues to investigate transcriptomic changes caused by osimertinib treatment.
Published in
Osimertinib induces reversible cardiac dysfunction through the GATA4-MYLK3-MYL2 axis
Zhang K, Ayala A, Norambuena-Soto I et al. · European heart journal 2026 · PMID 41330421 · doi:10.1093/eurheartj/ehaf813
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Also filed as BioProject PRJNA992391 and SRA study SRP447927. Searching any of these in the dataset finder brings you back here.

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