Specificity protein 6 governs human cytotrophoblast fate decisions and trophoblast stem cell establishment by targeting MSX2 regulatory elements [ChIP-seq]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 20 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 20 samples: 9 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE236794_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA992441 and SRA study SRP448072. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 18 samples.
How we read this: 9 replicated groups read from 20 sample titles; they account for 18 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7577174 G3M,CON,H3K27me3_rep1 G3M,CON,H3K27me3
- GSM7577175 G3M,CON,H3K27me3_rep2 G3M,CON,H3K27me3
- GSM7577176 G3M,SP6KO,H3K27me3_rep1 G3M,SP6KO,H3K27me3
- GSM7577177 G3M,SP6KO,H3K27me3_rep2 G3M,SP6KO,H3K27me3
- GSM7577178 G3M,CON,H3K4me3_rep1 G3M,CON,H3K4me3
- GSM7577179 G3M,CON,H3K4me3_rep2 G3M,CON,H3K4me3
- GSM7577180 G3M,SP6KO,H3K4me3_rep1 G3M,SP6KO,H3K4me3
- GSM7577181 G3M,SP6KO,H3K4me3_rep2 G3M,SP6KO,H3K4me3
- GSM7577182 G3M,CON,IgG
- GSM7577183 G3M,SP6KO,IgG
- GSM7577184 G3MS6G,HA_rep1 G3MS6G,HA
- GSM7577185 G3MS6G,HA_rep2 G3MS6G,HA
- GSM7951527 G3M,CON,H3K27ac_SI_rep1 G3M,CON,H3K27ac_SI
- GSM7951528 G3M,CON,H3K27ac_SI_rep2 G3M,CON,H3K27ac_SI
- GSM7951529 G3M,SP6KO,H3K27ac_SI_rep1 G3M,SP6KO,H3K27ac_SI
- GSM7951530 G3M,SP6KO,H3K27ac_SI_rep2 G3M,SP6KO,H3K27ac_SI
- GSM7951531 G3M,CON,P300_SI_rep1 G3M,CON,P300_SI
- GSM7951532 G3M,CON,P300_SI_rep2 G3M,CON,P300_SI
- GSM7951533 G3M,SP6KO,P300_SI_rep1 G3M,SP6KO,P300_SI
- GSM7951534 G3M,SP6KO,P300_SI_rep2 G3M,SP6KO,P300_SI
- GSE236796 Specificity protein 6 governs human cytotrophoblast fate decisions and trophoblast stem cell establishment by targeting MSX2 regulatory elements 42 samples shares msx2, cytotrophoblast, establishment, specificity, trophoblast, regulatory, decisions, targeting
- GSE236795 Specificity protein 6 governs human cytotrophoblast fate decisions and trophoblast stem cell establishment by targeting MSX2 regulatory elements [RNA-seq] 22 samples shares msx2, cytotrophoblast, establishment, specificity, trophoblast, regulatory, decisions, targeting
- GSE335690 Identifying PRMT1 target genes in human primary cytotrophoblasts 2 samples shares cytotrophoblast, trophoblast
- GSE281471 Targeting CD206+ macrophages disrupts the establishment of a key anti-tumor immune axis [Bulk RNA-seq] 243 samples shares establishment, targeting
- GSE270174 Trajectory modeling of first trimester placenta highlight differences between cytotrophoblast progenitors and trophoblast stem cells 50 samples shares cytotrophoblast, trophoblast
- GSE250585 Establishment and comparison of human term placenta-derived trophoblast cells 31 samples shares establishment, trophoblast
- GSE279087 Placental cytotrophoblast microvillar stabilization is required for cell-cell fusion 20 samples shares cytotrophoblast, trophoblast
- GSE270586 The specificity of gene activation was revealed by RNA-seq in the HEK293T cells transfected with the dCasMINI-VPR or dhpCasMINI-VPR system targeting IL1RN [RNA-seq] 18 samples shares specificity, targeting
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.