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Integrative Analysis of Genome-Wide Epigenetic and Transcriptomic Alterations Reveals Molecular Markers for Diagnosing Pediatric Obstructive Sleep Apnea in Black Females [WGBS]

GSE237279 Homo sapiens Methylation profiling by high throughput sequencing 18 samples Submitted 2024/12/02 Platform GPL24676
Summary
This study explores the epigentic and transcriptomic changes associated with pediatric obstructive sleep apnea in Black female patients. By analyzing saliva samples, the study identifies dysregulated pathways and specific molecular markers, emphasizing the need for accessible diagnostic tools and addressing healthcare disparities in underrepresented population. The non-invasive approach using saliva samples offers potential for future research and improved diagnostics for pediatric OSA.
Published in
Genome-wide epigenetic profiling and transcriptome analysis in pediatric Obstructive Sleep Apnea: A focus on Black female children
Koritala BSC, Parameswaran S, Donmez OA et al. · Heliyon 2024 · PMID 39717585 · doi:10.1016/j.heliyon.2024.e40830
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Direct links to NCBI, no account and no request form: the whole study as GSE237279_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 18 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA994520 and SRA study SRP449432. Searching any of these in the dataset finder brings you back here.

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