GEO series
Transcriptional profiling of striatum from a mouse model of Huntington's disease (Q140) crossed with Pms2 heterozygous and homozygous mice [Pms2_striatum]
GSE237584
Mus musculus
Expression profiling by high throughput sequencing
48 samples
2025/02/10
GPL24247
Summary
Striatum was isolated from 6-month-old Pms2+/- and Pms2-/- mice crossed with the Q140 knock-in (KI) HD mice and their respective controls. Transcriptomic analysis (RNASeq) was performed on 6 genotypes: WT, Q140, Pms2+/-, Q140 X Pms2+/-, Pms2-/-, and Q140 X Pms2-/-, 6-12 replicates per genotype.
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Paper (PMID 39938516) ↗
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