Effect of pyruvate (PA), lactate (LA), or 12-hydroxyeicosatetraenoic acid (12-HETE) stimulation on type1 conventional dendritic cells (cDC1) from the human ileum
RNA-seq (gene expression) · human · 16 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 16 samples: 4 × cDC1 cells, control vs 4 × cDC1 cells, PA vs 4 × cDC1 cells, LA vs 4 × cDC1 cells, 12-HETEGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- The pyruvate-GPR31 axis promotes transepithelial dendrite formation in human intestinal dendritic cellsProceedings of the National Academy of Sciences of the United States of America · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE240895_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1005658 and SRA study SRP455242. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 16 samples.
How we read this: 4 replicated groups read from 16 sample titles; they account for 16 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7711632 cDC1 cells, control_1 cDC1 cells, control
- GSM7711633 cDC1 cells, PA_1 cDC1 cells, PA
- GSM7711634 cDC1 cells, LA_1 cDC1 cells, LA
- GSM7711635 cDC1 cells, 12-HETE_1 cDC1 cells, 12-HETE
- GSM7711636 cDC1 cells, control_2 cDC1 cells, control
- GSM7711637 cDC1 cells, PA_2 cDC1 cells, PA
- GSM7711638 cDC1 cells, LA_2 cDC1 cells, LA
- GSM7711639 cDC1 cells, 12-HETE_2 cDC1 cells, 12-HETE
- GSM7711640 cDC1 cells, control_3 cDC1 cells, control
- GSM7711641 cDC1 cells, PA_3 cDC1 cells, PA
- GSM7711642 cDC1 cells, LA_3 cDC1 cells, LA
- GSM7711643 cDC1 cells, 12-HETE_3 cDC1 cells, 12-HETE
- GSM7711644 cDC1 cells, control_4 cDC1 cells, control
- GSM7711645 cDC1 cells, PA_4 cDC1 cells, PA
- GSM7711646 cDC1 cells, LA_4 cDC1 cells, LA
- GSM7711647 cDC1 cells, 12-HETE_4 cDC1 cells, 12-HETE
- GSE290640 Effect of knockdown of CCDC137 on gene expression in bladder carcinoma cell T24. 6 samples shares cdc1
- GSE267326 CCDC12 regulates selective shear of RBM47 to promote breast cancer progression 6 samples shares cdc1
- GSE213095 Positive feedback between cDC1s and CD8+ T cells typifies the inflammation of HLA-B27+ arthritis 46 samples shares cdc1
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.