P300 Regulates Histone Crotonylation and Preimplantation Embryo Development (ChIP-Seq)
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 22 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 22 samples: 22 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- P300 regulates histone crotonylation and preimplantation embryo developmentNature communications · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE241193_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1006717 and SRA study SRP455811. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 22 sample titles: 22 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7719142 Control H3K18cr MEF rep1 ChIP
- GSM7719143 Control H3K18cr MEF rep2 ChIP
- GSM7719144 Control H3K18cr Morula rep1 ChIP
- GSM7719145 Control H3K18cr Morula rep2 ChIP
- GSM7719146 Control H3K18cr Late-8-cell rep1 ChIP
- GSM7719147 Control H3K18cr Late-8-cell rep2 ChIP
- GSM7719148 Control POL(II) Late-8-cell rep1 ChIP
- GSM7719149 Control POL(II) Late-8-cell rep2 ChIP
- GSM7719150 P300 siRNA H3K18cr Late-8-cell rep1 ChIP
- GSM7719151 P300 siRNA H3K18cr Late-8-cell rep2 ChIP
- GSM7719152 P300 siRNA I1394G H3K18cr Late-8-cell rep1 ChIP
- GSM7719153 P300 siRNA I1394G H3K18cr Late-8-cell rep2 ChIP
- GSM7719154 P300 siRNA NaCr H3K18cr Late-8-cell rep1 ChIP
- GSM7719155 P300 siRNA NaCr H3K18cr Late-8-cell rep2 ChIP
- GSM7719156 P300 siRNA POL(II) Late-8-cell rep1 ChIP
- GSM7719157 P300 siRNA POL(II) Late-8-cell rep2 ChIP
- GSM8154269 Control H3K27ac Late-2-cell rep1 ChIP
- GSM8154270 Control H3K27ac Late-2-cell rep2 ChIP
- GSM8154271 Control H3K4me3 Late-8-cell rep1 ChIP
- GSM8154272 Control H3K4me3 Late-8-cell rep2 ChIP
- GSM8154273 P300 siRNA H3K4me3 Late-8-cell rep1 ChIP
- GSM8154274 P300 siRNA H3K4me3 Late-8-cell rep2 ChIP
- GSE269433 Histone Deacetylase 1 (HDAC1) maintains the transcriptome of embryonic stem cells through regulating acetylation at crucial genomic sites [ChIP-seq] 18 samples shares chip-seq, histone, embryo
- GSE309163 P300/CBP inhibition with gilteritinib and venetoclax targets leukemia stem cells in epigenetic mutant AML [ChIP-Seq] 16 samples shares p300, chip-seq
- GSE337703 p300/CBP inhibition promotes apoptosis in mouse embryos by impairing H1K75ac-mediated DNA repair from the 4-cell to blastocyst stage 8 samples shares p300, embryo
- GSE235109 Ensembles of genome-coverage single-cell histone modifications reveal epigenetic lineages during mouse preimplantation development 47 samples shares preimplantation, histone
- GSE291272 The placentalia specific histone H3.4 promotes germ cell development and reproductive fitness [ChIP-seq] 41 samples shares chip-seq, histone
- GSE310474 Cell autonomous regional differences in oligodendrocyte precursor cell development and response to oncohistone H3.3 K27M [ChIP-Seq] 40 samples shares chip-seq, histone
- GSE235005 Nutrient-driven histone code determines exhausted CD8+ T cell fates [ChIP-seq] 50 samples shares chip-seq, histone
- GSE278338 ChIP-seq to measure binding of NIPBL/MAU2, RAD21, and CTCF in mouse embryonic stem cells and neural progenitor cells 50 samples shares chip-seq, embryo
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.