P300/CBP inhibition with gilteritinib and venetoclax targets leukemia stem cells in epigenetic mutant AML [ChIP-Seq]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 16 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 16 samples: 16 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE309163_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1334251 and SRA study SRP627141. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 16 sample titles: 16 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9262388 FD AML, Control, 1, Input
- GSM9262389 FD AML, CCS1477, 1, Input
- GSM9262390 FD AML, Control, 2, Input
- GSM9262391 FD AML, CCS1477, 2, Input
- GSM9262392 FT AML, Control, 1, Input
- GSM9262393 FT AML, CCS1477, 1, Input
- GSM9262394 FT AML, Control, 2, Input
- GSM9262395 FT AML, CCS1477, 2, Input
- GSM9262396 FD AML, Control, 1, IP
- GSM9262397 FD AML, CCS1477, 1, IP
- GSM9262398 FD AML, Control, 2, IP
- GSM9262399 FD AML, CCS1477, 2, IP
- GSM9262400 FT AML, Control, 1, IP
- GSM9262401 FT AML, CCS1477, 1, IP
- GSM9262402 FT AML, Control, 2, IP
- GSM9262403 FT AML, CCS1477, 2, IP
- GSE309162 P300/CBP inhibition with gilteritinib and venetoclax targets leukemia stem cells in epigenetic mutant AML [RNA-Seq] 12 samples shares p300, cbp, aml, gilteritinib, inhibition, venetoclax, epigenetic, leukemia
- GSE233095 STAT3 inhibition permits epigenetic reprogramming and TLR9/IRF8-driven differentiation of inv(16) acute myeloid leukemia [RNASEQ_AML_CPGDOX] 12 samples shares aml, inhibition, epigenetic, leukemia
- GSE233096 STAT3 inhibition permits epigenetic reprogramming and TLR9/IRF8-driven differentiation of inv(16) acute myeloid leukemia [RNASEQ_AML_DECSCR] 12 samples shares aml, inhibition, epigenetic, leukemia
- GSE264627 CBP/P300 BRD Inhibition Reduces Neutrophil Accumulation and Activates Antitumor Immunity in TNBC 16 samples shares p300, cbp, inhibition
- GSE337703 p300/CBP inhibition promotes apoptosis in mouse embryos by impairing H1K75ac-mediated DNA repair from the 4-cell to blastocyst stage 8 samples shares p300, cbp, inhibition
- GSE250428 NAT10 promotes cancer metastasis by modulating p300/CBP activity through chromatin-associated tRNA [ChIP-seq] 23 samples shares p300, cbp
- GSE280521 p300/CBP-catalyzed acetylation safeguards minor zygotic genome activation via activating DUX [ChIPseq_ATAC-seq_Stacc-seq] 50 samples shares p300, cbp
- GSE250430 NAT10 promotes cancer metastasis by modulating p300/CBP activity through chromatin-associated tRNA 40 samples shares p300, cbp
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.