Vascular and perivascular cell profiling reveals the molecular and cellular bases of blood-brain barrier heterogeneity [GEOMx]
Spatial transcriptomics · mouse · 53 samples
- What it is
- Spatial transcriptomicsGene activity measured with its position in a tissue section.
- Organism
- Mus musculus (mouse)
- Samples
- 53 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Characteristics of blood-brain barrier heterogeneity between brain regions revealed by profiling vascular and perivascular cellsNature neuroscience · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE241199_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Spatial studies usually ship Space Ranger style folders (count matrix plus tissue images). Look for them among the supplementary files.
Also filed as BioProject PRJNA1006713 and SRA study SRP455848. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 53 more — browse all 53 samples with per-sample file links →
- GSE241206 Vascular and perivascular cell profiling reveals the molecular and cellular bases of blood-brain barrier heterogeneity 105 samples shares heterogeneity, perivascular, blood-brain, vascular, cellular, barrier, bases
- GSE325187 Senescent Endothelial Cells in Cerebral Microcirculation Are Key Drivers of Age-Related Blood-Brain Barrier Disruption, Microvascular Rarefaction, and Neurovascular Coupling Impairment in Mice 20 samples shares blood-brain, vascular, barrier
- GSE287964 A blood-brain barrier-like vascular gate limits immunotherapy efficacy in neuroendocrine cancers 12 samples shares blood-brain, vascular, barrier
- GSE229916 Pericytes and perivascular fibroblasts contribute to central nervous system fibrosis in a region dependent manner 832 samples shares perivascular, vascular
- GSE298799 Deconstructing the Intercellular Interactome in Vascular Dementia with Focal Ischemia for Therapeutic Applications 77 samples shares vascular, cellular
- GSE194224 Perivascular adipose tissue plasticity in response to angiotensin II 40 samples shares perivascular, vascular
- GSE248272 Therapeutically targeting perivascular macrophage effector function improves CD8+ T-cell infiltration and response to chemotherapeutic drugs in cancer 30 samples shares perivascular, vascular
- GSE199288 Perivascular fibrosis is mediated by a KLF10-IL-9 signaling axis in CD4+ T cells 27 samples shares perivascular, vascular
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.