GEO series
Effect of androgen receptor signaling on H3K27 trimethylation in Th17 cells
GSE241823
Mus musculus
Genome binding/occupancy profiling by high throughput sequencing
12 samples
2024/08/27
GPL24247
Summary
Females have increased prevalence of many Th17-mediated diseases, including asthma. Androgen signaling decreases Th17-mediated airway inflammation, and Th17 cells rely on glutaminolysis. However, it remains unclear whether androgen receptor (AR) signaling modifies glutamine metabolism to suppress Th17-mediated inflammation. In this experiment, we conducted a CUT & RUN to determine how AR signaling modified histone 3 lysine 27 trimethylation in Th17 cells from WT males, WT females, and ArTfm male mice (n=3 from each group).
Download
NCBI GEO page ↗
Paper (PMID 39404231) ↗
{# Names what the click gives you. "Open in finder" meant nothing to a
visitor who arrived from a search engine and has never seen the tool. #}
Find more
mouse ChIP / ATAC / CUT&Tag datasets →
Similar datasets
- GSE249984 Androgen receptor action in mouse granulosa cells in response to LH surge 14 samples
- GSE339012 Mega-Enhancers Compartmentalize Transcriptionally Active Long Genes in the Brain [ChIP-Seq] 22 samples
- GSE328495 Gene expression + ATAC profiling of trisomic hippocampal neurons upon SAHA treatment [ATAC-seq] 16 samples
- GSE324864 HP1B and H3K9me3 Regulate Olfactory Receptor Choice and 2 Transcriptional Identity [ChIP-seq] 28 samples
- GSE292285 Depletion of lamin-associated polypeptide 2 alpha leads to chromatin reorganization and redistribution of A-type lamins to open genomic regions [ChIP-seq] 22 samples
- GSE306458 ACVR1-mediated glycolytic reprogramming promotes histone lactylation and neuronal pyroptosis in neuropathic pain {ChIP-seq] 12 samples
- GSE306261 Astrocyte glucocorticoid receptor signaling restricts neuronal plasticity [CUT&RUN] 50 samples
- GSE163008 Loop extrusion by cohesin plays a role in enhancer-activated gene expression early in differentiation (ChIP-seq) 26 samples
Share this dataset
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.