MARK2/MARK3 kinases are catalytic co-dependencies of YAP/TAZ in human cancer [RNA-seq]
RNA-seq (gene expression) · human · 180 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 180 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- MARK2/MARK3 Kinases Are Catalytic Codependencies of YAP/TAZ in Human CancerCancer discovery · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE242516_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1013790 and SRA study SRP459042. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 180 more — browse all 180 samples with per-sample file links →
- GSE242517 MARK2/MARK3 kinases are catalytic co-dependencies of YAP/TAZ in human cancer 192 samples shares mark2, mark3, yap, taz, co-dependencies, catalytic, kinases
- GSE241897 MARK2/MARK3 kinases are catalytic co-dependencies of YAP/TAZ in human cancer [CUT&RUN] 12 samples shares mark2, mark3, yap, taz, co-dependencies, catalytic, kinases
- GSE318595 Physiological perfusion of human vasculature reveals a YAP/TAZ-Apelin switch linking intraluminal flow to endothelial state transitions and vessel remodeling [Bulk RNA-seq] 31 samples shares yap, taz, rna-seq
- GSE292598 YAPTAZ and neuroblastoma cell plasticity [RNA-Seq] 25 samples shares yap, taz, rna-seq
- GSE295181 HIF2ɑ Requires Engagement with YAP/TAZ and AP-1 Transcription Factors to Maintain Oncogenic Transcription in Clear Cell Renal Cell Carcinoma [RNA-Seq] 12 samples shares yap, taz, rna-seq
- GSE259388 YAP1/TAZ knockdown in melanoma 54 samples shares yap, taz
- GSE275995 YAP/TAZ cooperate with AP-1 to drive the mesenchymal cell state in neuroblastoma [RNAseq] 36 samples shares yap, taz
- GSE308636 Transcriptional changes mediated by the HDACi belinostat in IDH-mutant glioma cultures with YAP and TAZ overexpression 36 samples shares yap, taz
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.