MARK2/MARK3 kinases are catalytic co-dependencies of YAP/TAZ in human cancer [CUT&RUN]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 12 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 12 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- MARK2/MARK3 Kinases Are Catalytic Codependencies of YAP/TAZ in Human CancerCancer discovery · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE241897_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1010710 and SRA study SRP457503. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 12 more — browse all 12 samples with per-sample file links →
- GSE242517 MARK2/MARK3 kinases are catalytic co-dependencies of YAP/TAZ in human cancer 192 samples shares mark2, mark3, yap, taz, co-dependencies, catalytic
- GSE242516 MARK2/MARK3 kinases are catalytic co-dependencies of YAP/TAZ in human cancer [RNA-seq] 180 samples shares mark2, mark3, yap, taz, co-dependencies, catalytic
- GSE302452 Mutant RIT1 cooperates with YAP to drive an EMT-like lung cancer state [CUT&Run] 94 samples shares yap, cut, run
- GSE295183 HIF2ɑ Requires Engagement with YAP/TAZ and AP-1 Transcription Factors to Maintain Oncogenic Transcription in Clear Cell Renal Cell Carcinoma [CUT&Tag] 60 samples shares yap, taz, cut
- GSE330470 ChIP-seq and CUT&Tag profiling of the genome binding of YAP/TAZ-TEAD and SMAD3 in the human HCC cell line HCCLM3 [ChIP-seq] 55 samples shares yap, taz, cut
- GSE330469 ChIP-seq and CUT&Tag profiling of the genome binding of YAP/TAZ-TEAD and SMAD3 in the human HCC cell line HCCLM3 [CUT&Tag] 24 samples shares yap, taz, cut
- GSE235960 A non-canonical repressor function of JUN restrains YAP activity and suppresses YAP-dependent liver cancer growth [CUT&RUN] 64 samples shares yap, cut, run
- GSE275987 YAP/TAZ cooperate with AP-1 to drive the mesenchymal cell state in neuroblastoma [CnR] 42 samples shares yap, taz
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.